Solution of the phase problem for coherent scattering from a disordered system of identical particles. New Journal of Physics, Volume 15, January 2013, Article number 013059

While the implementation of single-particle coherent diffraction imaging for non-crystalline particles is complicated by current limitations on photon flux, hit rate and sample delivery, the concept of many-particle coherent diffraction imaging offers an alternative way of overcoming these difficulties. In this paper, we present a direct, non-iterative approach for the recovery of the diffraction pattern corresponding to a single particle using coherent x-ray data collected from a two-dimensional disordered system of identical particles; this approach does not require a priori information about the particles and can be applied to the general case of particles without symmetry. The reconstructed single-particle diffraction pattern can be directly used in common iterative phase retrieval algorithms to recover the structure of the particle. © IOP Publishing and Deutsche Physikalische Gesellschaft.



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Indexed keywords

Coherent diffraction imaging; Coherent X-rays; Current limitation; Disordered system; Hit rate; Identical particles; Iterative phase retrieval algorithm; Non-iterative; Phase problem; Photon flux; Priori information; Single-particle